Konzo outbreak in the Western Province of Zambia

Abstract Objective To identify the etiology of an outbreak of spastic paraparesis among women and children in the Western Province of Zambia suspected to be konzo. Methods We conducted an outbreak investigation of individuals from Mongu District, Western Province, Zambia, who previously developed lower extremity weakness. Cases were classified with the World Health Organization definition of konzo.…

Chronic Exposure to Cyanogens in Cassava: Evidence from Zambezia Province, Mozambique

Introduction  In Mozambique the first cases of konzo were  identified in 1981 in an epidemic with more than 1100 cases in northern Nampula Province. Since then the disease has been both epidemic and endemic in Nampula and neighbouring Zambézia Province. Monitoring in Nampula has shown continued cyanide exposure from cassava in both patients with demonstrated konzo,…

Inhambane region training in good manufacturing practice, hygiene and safety in cassava processing

About 17 groups of cassava processors were trained in good hygiene and safety practices in the processing of cassava roots in the Zavala and Inharrime districts in Inhambane province. During the training, processors were warned of practices that should be performed when working with bitter varieties in order to reduce the cyanide content of cassava…

President of the Republic inaugurates new PhilAfrica unit in Mozambique

The President of the Republic, Filipe Nyusi, inaugurated the new industrial unit of DADTCO Mandioca Mozambique in Inharrime, in the province of Inhambane. The company’s new production line, which specializes in the manufacture of cassava-based food products, represents a total investment of US $ 3 million in the modernization of two company factories in Ribáue,…

Konzo: a distinct neurological disease associated with food (cassava) cyanogenic poisoning

Epidemics of neurodegenerative diseases putatively caused by food toxins have been reported in the tropics with no clear understanding of their pathogenetic mechanisms. These diseases include the disease named Konzo that has been well documented in sub-Sahara Africa, mostly among children and women of childbearing age. Outbreaks of Konzo have occurred in the Democratic Republic…